Taking regular walks, eating a healthy diet, not smoking, and following guidelines for drinking alcohol will also help strengthen your bones. It is also used to treat early breast cancer in women who have experienced menopause and who have already been treated with a medication called tamoxifen (Nolvadex) for 5 years. Aromatase inhibitors may cause muscle and joint aches and pains. If you are at risk of developing osteoporosis, your doctor may prescribe drugs called bisphosphonate to protect your bones. Always tell your doctor or nurse about any change to your eyesight. Talk to your doctor if side effects from Arimidex are persisting despite stopping it. It’s best to take it at the same time every day. Casper says that about 1 percent of people who take letrozole get leg cramps and headaches, but the good news is that these symptoms go away once you stop taking the pills. Drink lots of fluids if you think you may have an infection. After menopause, estrogen is no longer made in the ovaries. Tell your doctor if this does not get better. The study also looked at how stopping hormonal therapy affected the women's risk of dying. Tell all of your health care providers that you take letrozole. If your eating problems do not improve, talk to your doctor or nurse. This is important to ensure that it is working as well as possible. Let your doctor or nurse know if you have headaches. Men with breast cancer may be given letrozole, although another drug called tamoxifen is more commonly used. Although not all of these side effects may occur, if they do occur they may need medical attention. What happens when you stop taking Letrozole? If letrozole stops working, your specialist may prescribe another hormone drug. Less common but more severe side effects of aromatase inhibitors are heart problems, osteoporosis, and broken bones. This includes medications that can be purchased in a store or pharmacy. Keep the pills in their original packaging at room temperature. Hot flashes and sweating can subside after the first few months. Along with its needed effects, letrozole may cause some unwanted effects. It can help to lower your intake of nicotine, alcohol, and hot beverages containing caffeine such as tea and coffee. If you have pain or pressure in your chest or feel out of breath at any time during or after treatment, let your doctor know immediately. Letrozole is taken once a day in tablet form. Withdrawal: Consult your gynecologist for a better way to discontinue your hormones. If you’re having chemotherapy or radiotherapy, your specialist will tell you when it’s best to start letrozole. In rare cases, women may have vaginal bleeding. This usually improves as your body adjusts to letrozole. How long after being disease-free from breast cancer is it safe to stop letrozole (Femara)? • If night sweats interfere with sleep, try taking your letrozole in the morning. It is very important that you do not stop taking letrozole without telling your doctor, as this may affect the success of the treatment. Keep using birth control for at least 3 weeks after your last dose of letrozole. They can prescribe painkillers and give you advice. Taking short walks regularly will help you feel less tired. Most side effects settle down a few months after taking letrozole or can be controlled or managed. Nausea is usually mild, but tell your doctor or nurse if this happens. Many types of breast cancer depend on the hormone estrogen to grow. HOT FLASHES AND SWEATING. Talk to your specialist or advice line before you stop taking a cancer drug. There is hope after this med! Yes this is a common reaction when you stop taking Femara. If you forget to take a pill, take one as soon as you remember. It is used to treat breast cancer in women who have gone through menopause. Letrozole is suitable for women who have been through the menopause and whose breast cancer is oestrogen receptor positive. If you have any worries or questions about taking or stopping letrozole, you can call us free on 0808 800 6000 to talk through your concerns. Talk to your nurse or doctor if you experience these changes so that they can give you support and. When you start to take letrozole, you may feel tired, drowsy, or feel like you have no energy. This medicine may increase the amount of cholesterol and fat in the blood. If you’re thinking about stopping taking letrozole for any reason, talk to your specialist first. Except when it is almost time for your next dose, do not take a double dose. Tell your doctor if you notice this or any other type of swelling. 6. Sometimes, doctors give letrozole before surgery to try to reduce the size of the cancer and avoid having to perform a mastectomy (removal of the breast). Letrozole is used after surgery and other treatments to reduce the risk of breast cancer returning. Some people worry about stopping their treatment, but there’s evidence that letrozole continues to reduce the risk of breast cancer coming back for many years after you stop taking it. You will normally have a bone density scan to check on the healthiness of your bones before and during the treatment. The level of drug in your body will remain high enough from the day before. 3. Who it’s suitable for Tell your doctor or nurse if this is a problem. Check with your doctor immediately if any of the following side effects occur while taking letrozole: Less common. Let your health professionals know if you have any of these symptoms. You may develop a mild skin rash. #1 is a problem with my hands, unable to make fists or grip a knife to cut meat, hands feeling swollen every morning. The pills are taken at the same time each day, either in the morning or at night. If you notice any changes in your heart rate, tell your doctor immediately. Do not stop: Letrozole ... Hi, i stopped taking femara (letrozole) two weeks ago - cold turkey and have been having a lot of headaches, dizziness, nausea, muscle and joint pains, tiredness? They can prescribe drugs to help control them and can also give you advice on managing side effects. 1. Letrozole can also cause indigestion or abdominal pain. Hot flashes and sweating can subside after the first few months. Use effective birth control if you are not past menopause. 7. If you have to go to the hospital for whatever reason other than cancer, always tell the doctors and nurses that you are taking letrozole. Bone fracture; breast pain; chest pain This is there any withdrawal after stop taking letrozole page on EmpowHER Women's Health works best with javascript enabled in your browser. Tell your doctor if your hot flashes become bothersome. Sometimes letrozole is given alongside a drug called goserelin (Zoladex) to women who haven’t yet been through the menopause. Letrozole is a hormone therapy drug. Your hair will thicken after the treatment ends. In the study, 13% of women stopped taking the drugs due to side effects such as joint and muscle pain. Do not stop taking letrozole unless your doctor instructs you to. 5. Arimidex (anastrozole) is a brand-name prescription drug that’s used for certain types of breast cancer. There are certain important things to remember when taking the tablets. Even though their ovaries have stopped producing estrogen, it is still produced by the aromatase enzyme found in other tissues. If your cancer is hormone receptor negative, then letrozole will not be of any benefit. Given that one in three patients taking tamoxifen or aromatase inhibitors eventually develop resistance, the researchers … I have another appt booked at the oncology clinic in early December so I will talk further about it with whomever I see at that time. Hospital Universitario Fundación Jiménez Díaz, Strategic plan of the Oncohealth Institute. This will depend on your individual circumstances, but letrozole is usually taken for five to ten years. When letrozole is given I have had several minor side effects, but 2 side effects that I deem as too important to continue taking the daily pill. Some women may discover that they feel down when taking letrozole. Letrozole is a drug used to treat breast cancer in women who have gone through the menopause. letrozole is for use only in women who can no longer get pregnant. 8. Hormones are substances produced naturally in the body. Let your doctor know if you have pain or discomfort when urinating, if you urinate more frequently than normal, or if your urine is cloudy or foul-smelling. These drugs, which include Arimidex (anastrozole), Aromasin (exemestane), and Femara (letrozole), are usually given to postmenopausal women. You should not stop taking Letrozole without discussing with your physician. It the side effects are very bothersome and are unmanageable, your oncologist may suggest you start on a different hormone therapy. just been taken off letrozole after one year and four years on tamoxifin It looks like you have javascript turned off. Healthy eating and staying physically active will help if you have worries about your weight. Let your doctor or nurse know if this happens. However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. I completed the full five years as prescribed. Your treatment team will tell you when to stop taking letrozole. Some people worry about stopping their treatment, but there’s evidence that exemestane continues to reduce the risk of breast cancer coming back for many years after you stop taking it. We’d love to keep in touch about news, events and how you can get involved. Posted: December 2, 2011; If you would like to reproduce some or all of this content, see Reuse of NCI Information for guidance about copyright and permissions. If you have any problems with the way your liver works, or any problems with the way your kidneys work. However, some side effects, such as high cholesterol, lymphedema, osteoporosis, and vaginal dryness may persist despite discontinuation of Arimidex. Tamoxifen may cause hot flashes. We have … If you're taking adjuvant hormonal therapy medicine now, stick with it as prescribed. Before taking this medicine. You can use non-hormonal creams, gels or lubricants to help with vaginal dryness and any discomfort during sex. Where to Purchase Femara (Letrozole)? They should be stored away from heat and direct sunlight. Taking letrozole for a number of years increases the risk of bone thinning (osteoporosis). Some people start taking letrozole after a few years of taking the hormone therapy drug tamoxifen. I had an estrogen cancer and I have been on letrozole for a year. These are common and tend to be mild, though they can vary. Non-hormonal creams and gels or lubricants can help reduce vaginal dryness and discomfort during sex. Your ankles and feel may swell up because of the build-up of fluid. Three months ago I started with bone and joint pain. Thanks for your thoughts, I think the reason the oncologist is asking me to stop taking Letrozole is to see if it is causing this painfully condition and until it's out of my system he does not know whether to change to another Al. These are common and tend to be mild, though they can vary. 2. No one responded to my post about this, so I'll try again: I've only been taking Femara, but I'm already wondering: so what happens in 5 or 10 years (new research shows we might have to be on this stuff longer) when we stop taking our aromatase inhibitors? This may increase the risk of bone fractures. Learn about side effects, warnings, dosage, and more. They may also recommend that you take calcium and vitamin D supplements. If you accidentally take too much letrozole (Femara), contact a doctor or hospital straight away.You might need medical treatment. You won’t need to stop taking it gradually. Letrozole is taken as a tablet once a day, with or without food. Sometimes, women have irritated eyes or blurred vision when taking letrozole. What is letrozole? There are a number of other brands of letrozole, all of which contain the same dose of the drug. Stopping Letrozole? when you first start taking letrozole. Try to pace yourself until this improves. Dr. Edward Smith answered. This medicine may make you dizzy, drowsy, or tired than they are normally. If this happens, your doctor may give you medicine to lower the cholesterol and fat in the blood. Letrozole works by reducing the amount of oestrogen made in the body. Hormone therapy is a very common treatment for secondary breast cancer and many people take it for a long time. If this happens, it is likely to occur in the first weeks of treatment or when changing from another hormone therapy to letrozole. Eating healthy meals and becoming more physically active can help you maintain a healthy weight. Low doses of certain antidepressants can help reduce hot flashes. Occasionally, letrozole may be used as the first treatment for breast cancer, for example when surgery isn’t appropriate or needs to be delayed. Do not take other drugs containing oestrogen, such as hormone replacement therapy (HRT), while you’re taking letrozole as this may interfere with its effectiveness. It is important to strike the correct balance between getting enough rest and staying physically active. You should not use letrozole if you are allergic to it. Do not start, stop, or change the dose of any drug without checking with your doctor. Let your doctor or nurse know if this happens. Letrozole can interact with other drugs. His feeling was that as there is no evidence that continuing Letrozole after 5 years is beneficial, I should stop taking it after December. Some breast cancers are stimulated to grow by the hormone oestrogen. Your doctor may check your cholesterol levels with a blood test. Letrozole is also used in women who have experienced menopause as a first treatment of breast … If you miss a dose, you don’t need to take an extra dose the next day. Physical activity and maintaining a healthy weight can help reduce joint pain and keep joints flexible. You can buy these from a chemist, or your doctor can prescribe them. It can also take several weeks or months to reverse bad sleeping habits caused by Arimidex. The half life of the drug is 2 days so it should be out of your system within 4 days. However, they may be more problematic for some women. Now 2 months later, without letrozole I am feeling much better. Your doctor will determine your dose and how long you will be taking Letrozole. Taking letrozole with other drugs. If you have any questions about this, talk to your doctor. #2 is possibly just the inability to bounce … Do not stop taking letrozole unless your doctor instructs you to. I know it's scary but I had an allergic reaction to letrozole and had to stop taking all my medication including my in gales and lanzaporole and then slowly introduced them back but not the letrozole I have now been put on exemestane and yes still have joint pain but if it's to bad I take paracetamol. I hope this helps. One more time/what happens when you stop AIs. These are known as oestrogen receptor positive or ER+ breast cancers. The amount of Letrozole that you will receive depends on many factors, including your general health or other health problems, and the type of cancer or condition being treated. These drugs are often prescribed after breast cancer surgery, chemotherapy or radiation therapy to help prevent a recurrence of the disease. These act as chemical messengers and help control the activity of cells and organs. Side effects of letrozole Some women notice that their hair thins out while they are taking letrozole. They can normally suggest ways to improve the side effects. It can also be given to treat breast cancer that has spread to another part of the body (secondary breast cancer), when it’s often given alongside another drug. Letrozole belongs to a group of drugs called aromatase inhibitors. How long will I have to take it? Get a new prescription before the one you have runs out, and keep track of holidays, when pharmacies may be closed. It can help to lower your intake of nicotine, alcohol, and hot beverages containing caffeine such as tea and coffee. You should take the right dose, not more or less. Some people worry about stopping their treatment, but there’s evidence that letrozole continues to reduce the risk of breast cancer coming back for many years after you stop taking it. If you are taking other drugs, you may have certain side effects that are not listed here. However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. For these reasons, before you start taking letrozole it is important that your doctor knows: If you have not yet gone through the menopause, or if there is a possibility you could be pregnant. Talk to your specialist, pharmacist or GP about any complementary therapies, herbal remedies or supplements you want to use before you start using them. If this is the case, make sure you talk to your cancer doctor or nurse. In this section, you can read about why it's so important to stick to your treatment plan and ways to handle possible difficulties in following radiation, chemotherapy, and hormonal therapy regimens. You may have bleeding when you start this treatment, or if you change to it from another treatment. You may experience some of the side effects mentioned here, though it is rare for a patient to have all of them. I stopped taking it a month ago cause My hips and shoulders felt like they were coming out my sockets. If you do not have much of an appetite, try eating small meals on a regular schedule and often. Letrozole can also be used to treat breast cancer that has come back (recurrence). Tell your doctor if you are taking any other medication. Unlike the drug clomiphene, which was prescribed in the past, letrozole doesn’t cause mood changes or affect the endometrial lining or cervical mucus. Sometimes it may be possible to change to another hormone drug. Doctors sometimes prescribe it before or after another type of hormone therapy. Do not use if you are pregnant. Tell your doctor or nurse if you have ever had problems with blood pressure. Which contain the same time every day it safe to stop taking it...., alcohol, spicy food, caffeine intake ( coffee, tea, colas, )... Called bisphosphonate to protect your bones inform your doctor or nurse if this a... ( Femara ) results of several different studies looking at how stopping hormonal altogether... Easily controlled with drugs different hormone therapy than 4 days to a group drugs! Cancer shouldn ’ t need to stop taking it a month ago cause my and... Also take several weeks or months to reverse bad sleeping habits caused by Arimidex • try taking your letrozole bedtime... 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